Metabolic Syndrome

Homeopathic medicinals within Diabin+ include a number of herbal phytomedicinals believed to lower blood glucose levels, and quintessential Branched Chain Amino Acids (BCAAs), which act to increase Insulin sensitivity within the circulatory system, increase appropriate fatty acid synthesis and may be indirectly involved with interleukin and interferon secretion by lymph cells. Indeed, recently BCAAs and other large neutral Amino Acids have been found to be beneficial when elevated within the blood plasma of diabetic individuals. BCAAs may also help to protect against hypertension and cardiovascular problems now known to be associated with diabetic onset.

The Prickly Pear (Opuntia steptacantha, commonly known as "Nopal" in Mexico) can be found in Diabin+ as well. In a study reported in Diabetes Care and later in the Science News, Vol. 133, No.4, January 1988, this particular desert cactus was shown to lower blood glucose and Insulin levels in diabetics, the authors believing that the Prickly Pear treatment may improve the ability of Insulin to efficiently stimulate the movement of glucose from the blood into body cells.

Diabin+ is a safe and effective formulation which is further strengthened with the addition of Växa's TriCardia+ (containing 32-Free Form Amino Acids) and Systemex, a Lactose-free Meal Replacement Drink containing Casein and Colostrum.

Indeed, newly published research indicates that there is now good and compelling reason to supply the body with milk-based proteins, especially those which are predominantly Casein in nature like those contained within the Systemex. In this French study originating from the Sainte-Marguerite Hospital in Marseille, a diet rich in Casein appears to actually protect subjects (non-obese mice who have a genetic predisposition for developing diabetes: NOD mice) from developing diabetes and then passing it on to their young. Specifically, Casein fed NOD female mice were protected against spontaneous diabetes and male NOD mice against acute Cyclosphosphamide or Cy-induced diabetes while also lessening the severity of insulitis.

Moreover, Casein has been found to exhibit the highest ratio of Total Essential Amino Acids to total Nitrogen of all foods and proteins reported by the FAO/WHO Expert Group.

The specific Amino Acid configuration of Casein just mentioned appears to effectively compete against the inflammatory cytokines response produced by the lymphocytes of the Immune System mentioned earlier, and may even reduce or circumvent the possibility of such an aberrant response, protecting beta cell integrity within the pancreas and the subsequent production of Insulin from amino acids derived from its structure. No other changes in the Immune System could account for these results. Such may also allow or ensure ß-cell "rest," a treatment strategy now of medical preference.

Interestingly, egg-based (albumin) proteins and other hydrolyzed proteins did not demonstrate this "protective" effect; Subjects fed albumin based proteins developed insulitis in 10 weeks. This is yet another strong reason for those who have a family history of diabetes, especially pregnant or lactating women and children, to supplement with Växa's Systemex & TriCardia+. Because of the autoimmune nature of diabetes, supplementation with Immune-Aid is also recommended. Immune-Aid+ is formulated to ensure T-cell integrity and subsequent appropriate dispersal of those cellular populations throughout the bloodstream.

The good news is that with appropriate medical and nutritional support of the Immune System, and early detection, diabetes may be controlled and possibly even prevented.

References:

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Arden SD; Roep BO; Neophytou PI; Usac EF; et al., "Imogen 38: a novel 38-kD islet mitochondrial autoantigen recognized by T cells from a newly diagnosed type 1 diabetic patient," Department of Clinical Biochemistry, University of Cambridge, Addenbrooke's Hospital, United Kingdom, J Clin Invest 1996 Jan 15;97(2):551-61.

Blackwood, A.L., M.D.; Manual of Materia Medica, Therapeutics and Pharmacology, Second Edition, Chicago, 1922. Birk OS; Douek DC; Elias D; Takacs K; et al., "A role of Hsp60 in autoimmune diabetes: analysis in a transgenic model, "Medical Research Council Clinical Sciences Centre, Royal Postgraduate Medical School, Hammersmith Hospital, London, United Kingdom, Proc Natl Acad Sci U S A 1996 Feb 6;93(3):1032-7.

Clark, John Henry, "Dictionary of Practical Materia Media," Ninth Edition, London, 1901. Dewey,W.A., M.D.; Practical Homeopathic Therapeutics, Third Edition, San Francisco, 1934.

Hancock WW; Polanski M; Zhang J; Blogg N; Weiner HL, "Suppression of insulitis in non-obese diabetic (NOD) mice by oral Insulin administration is associated with selective expression of interleukin-4 and -10, transforming growth factor-beta, and prostaglandin-E," Department of Pathology, New England Deaconess Hospital, Boston, Am J Pathol 1995 Nov;147(5):1193-9.

Hermitte L; Atlan-Gepner C; Payan MJ; Mehelleb M; Vialettes B, "Dietary protection against diabetes in NOD mice: lack of a major change in the Immune System," Service de Nutrition, Endocrinologie, Maladies metaboliques, Hospital Sainte-Marguerite, Marseille, France, Diabete Metab 1995 Oct; 21(4):261-8.

Hopkins BA; Rakes AH; Daniel TE; Zimmerman CA; Croom WJ Jr., "Effects of intraperitoneal L-leucine, L-isoleucine, L-valine, and L-arginine on milk fat depression in early lactation cows," Department of Animal Science, North Carolina State University, J Dairy Sci 1994 Apr;77(4):1084-92.

Huges, Richard, M.D., "Principles and Practice of of Homeopathy," fourth edition, London, 1901. Johnson-Tardieu JM; Walworth EW; Cornelius JG; Ye X; et al., "Autoimmune diabetes-prone NOD mice express the Lyt2 alpha (Lyt2.1) and Lyt3 alpha (Lyt3.1) alleles of CD8,"Department of Pathology & Laboratory Medicine, University of Florida College of Medicine, Immunogenetics 1996;43(1-2):6-12.

Kendrew, Sir John; "The Encyclopedia of Molecular Biology," Blackwell Publishers, Oxford, Oxfordshire, England, 1994.

Pieper GM; Jordan M; Adams MB; Roza AM, "Syngeneic pancreatic islet transplantation reverses endothelial dysfunction in experimental diabetes," Department of Transplant Surgery, Medical College of Wisconsin, Diabetes 1995 Sep;44(9):1106-13.

Ruilope LM, "Effects of angiotensin converting enzyme inhibitors on the progression of diabetic nephropathy." Unidad de Hipertension, Hospital 12 de Octubre, Madrid, Spain, J Hypertens Suppl 1995 Aug;13(2):S91-3.

Takacs K; Douek DC; Altmann DM, "Exacerbated autoimmunity associated with a T helper-1 cytokine profile shift in H-2E-transgenic mice," Clinical Sciences Centre, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK, Eur J Immunol 1995 Nov; 25 (11):3134-41. Zipris D; Greiner DL; Malkani S; Whalen B; et al., "Cytokine gene expression in islets and thyroids of BB rats. IFN-gamma and IL-12p40 mRNA increase with age in both diabetic and Insulin-treated nondiabetic BB rats," Department of Medicine, University of Massachusetts Medical Center, J Immunol 1996 Feb 1;156(3):1315-21.